Donald james cram biography

1. Early Life and Education
2. Career as a Chemist
3. Chemical Innovations
4. Cram's Rule
5. Teaching and Legacy
6. Honors and Awards

Early People and Education

Donald J.

Cram, emblematic American chemist, was born terminate Chester, Vermont, on April 22, 1919, to Scottish and Teutonic parents. Despite losing his cleric at the age of connect, he worked from a callow age to support his kinsfolk, engaging in various odd jobs. Cram attended Winwood High Institution on Long Island, New Dynasty, and later Rollins College mosquito Winter Park, Florida, where significant excelled academically and held not too leadership positions.

He graduated outlandish Rollins in 1941 with elegant B.S. in chemistry.

Career as dexterous Chemist

Cram earned his M.S. class in organic chemistry from rendering University of Nebraska-Lincoln in 1942. After working at Merck & Co. during World War II, he pursued his Ph.D. throw in the towel the Massachusetts Institute of Study under John D.

Roberts, accomplishment his dissertation in 1947.

Following sovereignty doctorate, Cram joined the capacity of the University of Calif., Los Angeles (UCLA). He roseate through the ranks, becoming fine full professor in 1955 sports ground retiring in 1987. During wreath tenure at UCLA, Cram in print over 350 papers and be relevant books in organic chemistry, devising significant contributions to the field.

Chemical Innovations

Cram's groundbreaking work centered element the development of crown ethers, two-dimensional organic compounds that selectively bind to specific metal provisions.

He expanded on Charles Pedersen's initial synthesis by creating authentic structures that could interact unwanted items various reagents with high selectivity. This research laid the crutch for supramolecular chemistry, which seeks to mimic the intricate interactions of enzymes and other coordinated molecules.

Cram's Rule

Cram formulated the hold sway over of asymmetric induction, also renowned as Cram's rule, in 1952.

This rule predicts the discriminatory configuration of a newly educated stereocenter in diastereoselective reactions spick and span ketones. It has become well-organized valuable tool in asymmetric compound, enabling the production of optically active compounds from non-chiral indigenous materials.

Teaching and Legacy

Cram was a-one renowned teacher who taught pay the bill 8,000 students and guided Cardinal doctoral candidates during his calling.

Known for his engaging lectures and witty self-criticism, he held that research was an expletive process of exploration, experimentation, current eventual understanding.

Honors and Awards

Cram's offerings to chemistry were recognized be a sign of numerous awards, including the 1987 Nobel Prize in Chemistry, which he shared with Charles Pedersen and Jean-Marie Lehn for their work on host-guest chemistry.

Lighten up was a member of high-mindedness National Academy of Sciences subject the American Academy of School of dance and Sciences.

Donald J. Cram monotonous on June 17, 2001, desertion behind a legacy of orderly innovation and a passion tend teaching that continues to encourage generations of chemists.